QuickDoc.

General screening

·         50 to 70 invited every three years

·         > 70 GP can refer to local screening unit

Primary care management only

If the FHx shows only one 1^st degree or 2^nd degree relative diagnosed with breast cancer @  > 40, provided that none of the following is present in FHx:

·         Bilateral breast cancer

·         Male breast cancer

·         Ovarian cancer

·         Jewish ancestry

·         Sarcoma in a relative younger than age 45y

·         Glioma or childhood adrenal cortical carcinomas

·         Complicated patterns of multiple cancers at a young age

·         Paternal history of breast cancer (two or more relatives on the father’s side of the family)

Refer to the breast service [for initial screening, then if needed to the genetics services]

·         One 1^st degree F relative diagnosed with breast cancer at < 40y

·         One 1^st degree M relative diagnosed with breast cancer at any age

·         One 1^st relative with bilateral breast cancer where the first primary was diagnosed at younger than age < 50y

·         Two 1^st degree relatives, or one 1^st degree and one 2^nd relative, diagnosed with breast cancer at any age

·         One 1^st degree or 2^nd degree relative diagnosed with breast cancer at any age and one 1^st degree or 2^nd degree relative diagnosed with ovarian cancer at any age [one of these should be a 1^st degree relative]

·         Three 1^st degree or 2^nd degree relatives diagnosed with breast cancer at any age

Degrees

·          1^st  – Relatives share half of their genes with the person – [parents, brother, sister,  or child]

·         2^nd – Relatives shares about one quarter of their genes with the person –  [uncle, aunt, nephew, niece, grandparent, grandchild or half-sibling]

·         3^rd – Relatives share about one eighth of their genes with the person – [first cousin, great-grandparent or great-grandchild]

Detailed information: http://www.patient.co.uk/doctor/familial-breast-cancer